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Methotrexate Tablets IP 10 mg is a medication commonly used to treat a variety of conditions, including certain cancers (such as leukemia, lymphoma, and breast cancer), autoimmune diseases (like rheumatoid arthritis, psoriasis, and Crohn’s disease), and ectopic pregnancy. Methotrexate is an antimetabolite and folate antagonist that works by inhibiting the enzyme dihydrofolate reductase, which is essential for DNA synthesis and cell division. This disruption slows down the growth of cancer cells and reduces inflammation in autoimmune conditions.

The 10 mg dosage is usually taken once a week for conditions such as rheumatoid arthritis and psoriasis, or as part of a chemotherapy regimen for cancer treatment. Common side effects may include nausea, mouth sores, liver toxicity, fatigue, and low blood cell counts. Regular monitoring, including blood tests and liver function tests, is important to ensure the safe use of Methotrexate and to manage any potential side effects.