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Methotrexate Tablets IP 15 mg is a medication used to treat various conditions, including certain types of cancer (such as leukemia, lymphoma, and breast cancer), autoimmune diseases (like rheumatoid arthritis, psoriasis, and Crohn’s disease), and ectopic pregnancy. Methotrexate is an antimetabolite and folate antagonist that works by inhibiting the enzyme dihydrofolate reductase, which is necessary for DNA synthesis and cell division. This action helps slow the growth of cancer cells and reduces inflammation in autoimmune conditions.

The 15 mg dosage is typically used for more severe cases of the conditions being treated and is often taken once a week. For cancer treatment, Methotrexate may be part of a combination therapy regimen. Common side effects may include nausea, mouth sores, liver toxicity, fatigue, and low blood cell counts. Regular monitoring through blood tests and liver function tests is essential to manage any potential side effects and to ensure the drug’s effectiveness.