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Methotrexate Tablets BP 2.5 mg is a medication used to treat a variety of conditions, including certain types of cancer, autoimmune diseases (such as rheumatoid arthritis and psoriasis), and ectopic pregnancy. It is an antimetabolite and folate antagonist that works by inhibiting the enzyme dihydrofolate reductase, which is essential for DNA synthesis and cell division. This action slows the growth of cancer cells and suppresses immune system activity in autoimmune conditions.

The 2.5 mg dosage is typically taken on a weekly basis for conditions like rheumatoid arthritis and psoriasis, whereas for cancer treatment, it may be prescribed as part of a larger regimen. Common side effects include nausea, mouth sores, fatigue, liver enzyme changes, and low blood cell counts. Regular monitoring, including blood tests and liver function tests, is essential to minimize the risk of adverse effects.