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Methotrexate Tablets IP 7.5 mg is a medication used in the treatment of various conditions, including certain cancers (like leukemia and lymphoma), autoimmune diseases (such as rheumatoid arthritis, psoriasis, and Crohn’s disease), and ectopic pregnancy. Methotrexate is an antimetabolite and folate antagonist that inhibits the enzyme dihydrofolate reductase, which is crucial for DNA synthesis and cell division. By interfering with these processes, it helps slow down the growth of cancer cells and reduces inflammation in autoimmune conditions.

The 7.5 mg dosage is typically taken weekly for conditions like rheumatoid arthritis and psoriasis, though for cancer treatment, it may be prescribed as part of a broader chemotherapy regimen. Common side effects include nausea, mouth sores, liver toxicity, fatigue, and low blood cell counts. Regular monitoring through blood tests and liver function tests is important to manage potential side effects and ensure the medication is effective.